| 121 | Royal Edible Company | Thrissur | Partnerships | Other | Product | EE | EL | ME | IE | AU | MC | 2 | 9000 | | |
| 122 | Royal Enfield Veliyathu Motors | Vazhappily | Partnerships | Mechanical | Service | AU | 10 | 8000 | | |
| 123 | Safa Constructions Pvt Ltd | Ernakulam | Private Limited | Civil | Service | CE | 1 | 8000 | | |
| 124 | Saly Projects Pvt Ltd | Poonjar | Private Limited | Civil | Product | Process | Service | CE | 8 | 8000 | | |
| 125 | Saranga Geosoftware & Engineering Services Pvt.Ltd | Ernakulam | Private Limited | Computer/IT | Service | CT | EL | 50 | 10000 | | |
| 126 | SARON INNOVATURE LABS LLP | OTTAPALAM | Partnerships | Electronics | Product | Process | Service | EL | 2 | 8000 | | |
| 127 | Seonex Power Solution | KOTTAYAM | Sole Proprietorship | Electrical | Product | EE | EL | 4 | 8000 | | |
| 128 | SFO Technologies | Aluva | Private Limited | Electronics | Product | EE | 50 | 8000 | | |
| 129 | SFO Technologies Pvt Ltd | Kalamassery | Private Limited | Electronics | Product | CT | EE | EL | 150 | 10000 | | |
| 130 | Shantmi Homes | Changanacherry | Sole Proprietorship | Civil | Product | Process | Service | CE | EE | 12 | 8000 | | |
| 131 | SHREE SURYA TECHNOLOGIES | bangalore | Sole Proprietorship | Electrical | Product | EE | ME | MC | 20 | 15000 | | |
| 132 | Sirius Engineering Private Limited | Coimbatore | Private Limited | Mechanical | Product | ME | MC | 10 | 8000 | | |
| 133 | Skyline Builders | Palarivattam | Partnerships | Civil | Product | CE | 1 | 8000 | | |
| 134 | SMEC AUTOMATION PRIVATE LIMITED | Cochin | Private Limited | Electrical | Product | Service | CE | CB | CT | EE | EL | ME | IE | RA | AM | MC | 75 | 8000 | | |
| 135 | Southern Chips and Circuits Pvt Ltd | Bangalore | Private Limited | Electronics | Product | Service | EL | ME | 15 | 10000 | | |
| 136 | Southern plastics | Thalore, Thrissur | Private Limited | Polymer | Product | ME | 4 | 8000 | | |
| 137 | Sqft Builders | Thrissur | Sole Proprietorship | Civil | Service | CE | 6 | 10000 | | |
| 138 | St.Francis press | Ernakulam | Partnerships | Printing | Service | PT | 2 | 8000 | | |
| 139 | ST.THOMAS RUBBER INDUSTRY | KOTTAYAM | Sole Proprietorship | Polymer | Process | CH | 3 | 8000 | | |
| 140 | STERLING PRINT HOUSE PVT.LTD | ERNAKULAM | Private Limited | Printing | Service | PT | 4 | 8000 | | |